BRUSSELS and ATLANTA, March 16, 2023 /PRNewswire/ -- UCB, a global biopharmaceutical company, today announced that it will present eight bimekizumab abstracts across a range of IL-17 mediated diseases1,2 – moderate to severe plaque psoriasis, active psoriatic arthritis (PsA), and moderate to severe hidradenitis suppurativa (HS) – at the 2023 American Academy of Dermatology (AAD) Annual Meeting in New Orleans, U.S., March 17–21. The abstracts have been accepted as one late-breaking oral platform presentation and seven posters, including three with oral presentations. The platform presentation will share the first detailed data from the two Phase 3 studies, BE HEARD I and BE HEARD II, evaluating the efficacy and safety of bimekizumab compared with placebo in the treatment of adults with moderate to severe HS.3,4
"The Phase 3 results for hidradenitis suppurativa further demonstrate UCB's dedication to improving treatment options for patients with chronic diseases and reinforce our commitment to advancing dermatological care through cutting-edge science," said Emmanuel Caeymaex, Executive Vice President, Immunology Solutions and Head of U.S., UCB.
In the U.S., the efficacy and safety of bimekizumab have not been established for any indication and it is not approved by the U.S. Food and Drug Administration.
Five of the eight abstracts at AAD 2023 will share data on bimekizumab in the treatment of moderate to severe plaque psoriasis, including data evaluating bimekizumab in the treatment of nail psoriasis from the BE RADIANT Phase 3b trial. Two abstracts evaluating bimekizumab for the treatment of active PsA will also be presented.
The following is a guide to the UCB-sponsored abstracts at AAD 2023:
Notes to editors:
Bimekizumab is a humanized monoclonal IgG1 antibody that is designed to selectively inhibit both interleukin 17A (IL-17A) and interleukin 17F (IL-17F), two key cytokines driving inflammatory processes.5,6 In the U.S., the efficacy and safety of bimekizumab have not been established for any indication and it is not approved by the U.S. Food and Drug Administration.
In August 2021, bimekizumab was first approved in the European Union (EU)/European Economic Area (EEA) and in Great Britain, for the treatment of moderate to severe plaque psoriasis in adults who are candidates for systemic therapy.5,7 The label information may differ in other countries where approved. Please check local prescribing information.
For further information, contact UCB:
U.S. Communications, Immunology
UCB, Brussels, Belgium (www.ucb.com), is a global biopharmaceutical company focused on the discovery and development of innovative medicines and solutions to transform the lives of people living with severe diseases of the immune system or of the central nervous system. With approximately 8,600 people in approximately 40 countries, the company generated revenue of €5.5 billion in 2022. UCB is listed on Euronext Brussels (symbol: UCB). Follow us on Twitter: @UCBUSA.
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