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TOTOWA, N.J., June 10, 2016 /PRNewswire/ -- BiologicTx^® today announced the enhanced release of their Paired Donation Software, BiologicTx MatchGrid™ which includes a brand new feature called Knockout Avoids.  Knockout Avoids provides virtual desensitization by simulating the removal of incompatible antibodies, which can be barriers to transplantation.  Other enhancements include the integration of FileTool allowing greater patient data management, and an overall new design for a friendlier user experience.  BiologicTx MatchGrid 5.0 is being unveiled at the 2016 American Transplant Congress (ATC) in Boston, Massachusetts from June 11^th through 15^th at BiologicTx booth number 312.

Knockout Avoids
The Knockout Avoids feature is a brand new enhancement to BiologicTx MatchGrid.  Knockout Avoids allows the clinician to review patients that are near-miss matches to transplant that may become viable matches with the removal of incompatible antibodies (avoids).  Using Knockout Avoids, the clinician can then simulate the removal of incompatible antibodies via virtual desensitization and show potential new matches with donors as a result.  By simulating desensitization and virtually removing the incompatible antibodies, clinicians can identify more potential donor and recipient pairs, thereby increasing the opportunity for living donor transplant.  All of the data corresponding to Knockout Avoids can be viewed in real-time and can be assessed on a global or individual patient basis. 

Additional new enhancements to BiologicTx MatchGrid include:

• ABOi Feature allowing for virtual match identification across blood types
• New Match Flag that shows in real-time new potential matches as a result of changes to patient data providing immediate feedback for informed patient pool decisions

FileTool Integration
FileTool is a stand-alone application used in conjunction with BiologicTx MatchGrid where patient data is stored and managed.  In previous versions of BiologicTx MatchGrid, the user was made to toggle between the two different software packages for full utilization of MatchGrid.  In MatchGrid 5.0, FileTool has been integrated into the browser to allow for a friendlier user experience.  With the integration, users are now able to more easily import and manually enter patient data, edit or delete and set statuses in patient data, aggregate data more efficiently, and have the option to share either individually selected patients or all personal preferences.  This enhancement provides clinicians with granular control of their patients' data and provides real-time feedback regarding any changes in patient data.

"Software development is a very precise, black and white science; however, identifying potential kidney donor and recipient pairs is more of a gray area.  It requires the same level of precision but there are many more variables to consider when dealing with the human immune system," stated David Jacobs, Chief Technology Officer at BiologicTx.  "To develop the Knockout Avoid feature for MatchGrid, we created multiple custom algorithms to address all of the possible conflicting barriers to identifying potential matching pairs."

Darrin Carrico, President of BiologicTx commented, "Today, ABOi and living donor desensitization are performed on a limited basis due to the amount of manual scientific resources required.  The virtual desensitization and ABOi capabilities of MatchGrid will enable transplant centers to intelligently match patients within their internal and shared pools that require modest therapeutic interventions.  We will continue to develop and evolve the MatchGrid for domestic and international use, ultimately with the reward of seeing more people transplanted."

About BiologicTx MatchGrid™
BiologicTx Paired Donation's MatchGrid is an advanced enterprise software application that provides doctors and clinicians with the tools necessary to rapidly and accurately match living organ donors with patients who have willing, healthy but incompatible donors.  Using advanced matching and optimization algorithms, for a single center, MatchGrid can evaluate all potential matches from 2-way all the way through 12-way combinations in minutes or even longer regional chains, saving transplant centers months of work previously required to assess a smaller number of pairs.  The software can also optimize the number of transplants for a given pool of donor/recipient pairs, ensuring the maximum number of transplants for the most difficult people to match, with the highest quality matches for each transplant hub in a paired kidney donation network.

About BiologicTx^®
BiologicTx^® was founded as the first, solely focused infusion and pharmacy provider of biologic and oral transplant therapy management.  Since then, BiologicTx has expanded its services to integrate transplant therapies paired with digital health technology, providing a complete representation of the patient's response to therapy.  Our team is comprised of dedicated professionals that strive to advance desensitization, immunosuppressive, and rejection treatments worldwide, resulting in progressive and favorable patient outcomes.  We deliver efficient, start to finish services that establish therapeutic services in the home and clinic.  These services act in concert with the transplant center medical team.  In doing so, we provide hope and a better quality of life to our patients.  For more information, visit us at: www.BiologicTx.com.

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SOURCE BiologicTx